anti-Titin-Antibody - ELISA

EA601/48

Enzyme immunoassay for the quantitative determination of
anti-Titin antibodies in serum or plasma
 

48 (6x8) determinations, single break apart wells
 

100 µl 1:101 prediluted patient sera
performance within approximately 2 hours

Neurology, Immunology, autoimmune diseases

Paraneoplastic myasthenia gravis, thymic epithelial tumor, thymic carcinoma
 

First measurements with sera from patients with thymoma gave values between factor 2 to 4  ODsample/ODcalibrator

95 % of the patients with epithelial and malignant thymoma

significantly more specific than the determination of anti-    bodies against striated muscle by immunofluorescence
  - recombinant MGT30 peptide for antigen
  - reliable differentiation from thymic hyperplasia
  - simple and quick handling, incubation time 2 hours