Product Information

Insulin Antibody - RIA

Catalog-No.

RA107/50 and RA108/100
Radio Immuno Assay
for the quantitative determination of
antibodies against Insulin in serum
 

Format

50 or 100 Determinations

Procedure

20 µl of patient serum
Precipitation with anti-human-IgG
4 Standards, 2 Positive Controls, lyophilized; 1 Negative Control ready for use
Incubation over-night
 

Clinical Fields

Internal medicine, immunology, endocrinology

Diseases

Insulin-dependent diabetes mellitus (IDDM)

Normal Value

Negative < 0.4 u/mL; Positive 0.4 u/mL

Specificity

100% (n=100) of healthy blood donor sera samples gave values of less than 0.4 units per mL.

Sensitivity

Out of 62 type 1 DM patients who had never received insulin treatment, 21 (34%) were positive
for IAb. However, in patients who have received insulin treatment, IAb prevalence is much higher suggesting that insulin antibodies are being induced by insulin treatment in many patients.

Characteristics