MuSK Antibody - RIA
125I-Radioimmunoassay for the quantitative determination of MuSK Autoantibodies in Serum
Sample: 2 x 5 µl patient serum
1. Inkubation: Overnight (16-20 hours) at room temperature (20-25°C)
Neurology, Immunology, Autoimmune diseases
Acetylcholine receptor autoantibodies (AChRAb) seronegative Myasthenia gravis (MG)
Healthy blood donors < 0.05 nmol/l
Sera from 50 individual healthy blood donors were assayed in the MuSK Ab RIA. 50 (100%) were identified as beeing negative for MuSK Ab.
Serum samples from 18 patients with clinical symptoms of MG but negative for AChR Ab were assayed in the MuSK AB RIA. 18 (100%) were positive for MuSK Ab.