Product Information

MuSK Antibody - RIA

Catalog-No.

RA120/25

125I-Radioimmunoassay for the quantitative determination of MuSK Autoantibodies in Serum

Format

25 Determinations

Procedure

Sample: 2 x 5 µl patient serum

1. Inkubation: Overnight (16-20 hours) at room temperature (20-25°C)

2. Inkubation: 2 hours at 2-8°C

Clinical Fields

Neurology, Immunology, Autoimmune diseases

Diseases

Acetylcholine receptor autoantibodies (AChRAb) seronegative Myasthenia gravis (MG)

Normal Value

Healthy blood donors < 0,05 nmol/l

Specificity

Sera from 50 individual healthy blood donors were assayed in the MuSK Ab RIA. 50 (100%) were identified as beeing negative for MuSK Ab.

Sensitivity

Serum samples from 18 patients with clinical symptoms of MG but negative for AChR Ab were assayed in the MuSK AB RIA. 18 (100%) were positive for MuSK Ab.

Instruction Sheet